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API Intermediates

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Inspect pharmaceutical intermediates in real-time stereochemical 3D. Rotate, zoom, and analyze molecular geometry, bond angles, and regulatory monographs.

Carbon (C) Nitrogen (N) Oxygen (O) Sulfur (S) Chlorine (Cl) Hydrogen (H)

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Portfolio

API Intermediates

Pharmaceutical intermediates are building blocks used in the synthesis of APIs. Our portfolio covers intermediates for Domperidone, Olmesartan, Telmisartan, Loperamide, Donepezil and many more.

Related API / Product
Intermediate
CAS No.
Therapeutic use
Alcaftadine
N-Methyl-4-chloro piperidine
5570-77-4
Antihistamine
Amitriptyline HCl & Nortriptyline HCl
Dibenzosuberone
1210-35-1
Antidepressant
Amitriptyline HCl & Nortriptyline HCl
3-(N,N, di methyl amino) propylchloride HCl
5407-04-5
Antidepressant
Bepotastine Besilate
N-carbethoxy-4-hydroxypiperidine
65214-82-6
Antihistamine
Bepotastine Besilate
(4-Chlorophenyl)(pyridin-2-yl)methanol
27652-89-7
Antihistamine
Bepotastine Besilate
(4-Chlorophenyl)(pyridin-2-yl)methanone
122368-54-1
Antihistamine
Bepotastine Besilate
2-((4-Chlorophenyl)(4-piperidinyloxy)methyl)pyridine
5382-16-1
Antihistamine
Bepotastine Besilate
4-[(4-Chlorophenyl)-2-pyridylmethoxy]piperidine p-nitrobenzoic acid salt
161558-45-8
Antihistamine
Cinnarizine and Flunarizine
1-(Diphenyl methyl) piperazine
841-77-0
Antihistamine
Cyclobenzaprine HCl
Dibenzosuberenone
2222-33-5
Muscle Relaxant
Cyclobenzaprine HCl
3-(N,N Di methyl amino) propylchloride HCL
5407-04-5
Muscle Relaxant
Cyproheptadine HCl
Dibenzosuberenone
2222-33-5
Anti-allergic
Cyproheptadine HCl
N-Methyl-4-chloro piperidine
5570-77-4
Anti-allergic
Dabigatran Etexilate Mesylate
3-[[[2-[[(4-Cyanophenyl)amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]pyridin-2-ylamino]propionic acid ethyl ester
211915-84-3
Antithrombotic
Dabigatran Etexilate Mesylate
N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-beta-alanine ethyl ester
429658-95-7
Antithrombotic
Dabigatran Etexilate Mesylate
Ethyl 3-(((2-(((4-((((hexyloxy)carbonyl)amino)iminomethyl)phenyl)amino)methyl)-1-methyl-1H-benzimidazol-5-yl)carbonyl)(pyridin-2-yl)amino)propanoate
211915-06-9
Antithrombotic
Domperidone
1-(3-Chloropropyl)-1,3-dihydro-1H-benzimidazol-2-one
62780-89-6
Antiemetic
Domperidone
5-Chloro 1,3 dihydro -1- (4-piperidinyl) -2H- benzimidazol - 2 -one
53786-28-0
Antiemetic
Donepezil HCl
4-[(5,6-Dimethoxy-1-indanon-2-yl)methyl]piperidine
120014-30-4
Anti-alzheimer
Donepezil HCl
5,6-dimethoxy-2-(pyridin-4-yl)-methylene-indan-1-one
4803-74-1
Anti-alzheimer
Donepezil HCl
(2RS)-2-[(1-Benzylpiperidin-4-yl)-5, 6-dimethoxy-2, 3- dihydro-1H-inden-1-one (Base)
120014-06-4
Anti-alzheimer
Ebastine
4-Tert butyl-4-chlorobutyrophenone
43076-61-5
Antihistamine
Eprosartan
2-Butyl-1H-imidazole-5-carboxaldehyde
68282-49-5
Antihypertensive
Febuxostat
Ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
161797-99-5
Antihyperuricemic
Febuxostat
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
161798-01-2
Antihyperuricemic
Febuxostat
Ethyl 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
161798-02-3
Antihyperuricemic
Febuxostat
Ethyl-2-(3-Formyl-4-isobutoxy phenyl)-4-methyl-1,3-thiazole-5-carboxylate
161798-03-4
Antihyperuricemic
Febuxostat
Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
160844-75-7
Antihyperuricemic
Flunarizine Di-HCl
1-[bis(4-fluorophenyl)methyl]piperazine (OR) 4,4'-Difluorobenzhydrylpiperazine
27469-60-9
Antihistamine
Golvatinib & Gilteritinib
1-N-Methyl-4-(4-piperidin-4-yl)-piperazine
53617-36-0
Anticancer
Haloperidol
4-Chloro-4'-fluoro-butyrophenone
3874-54-2
Antipsychotic
Haloperidol
4-(4-Chlorophenyl)-4-hydroxy piperidine
39512-49-7
Antipsychotic
Indoramin HCl
4-Benzamido piperidine
33953-37-6
Antiadrenergic
Ketotifen
N-Methyl-4-chloro-piperidine
5570-77-4
Antihistamine & Anti-allergic
Linagliptin
(R)-3-(boc-amino) piperidine
309956-78-3
Antidiabetic
Linagliptin
(R)-3-Piperidinamine dihydrochloride
334618-23-4
Antidiabetic
Loperamide HCl
4-(4-Chlorophenyl)-4-hydroxy piperidine
39512-49-7
Antidiarrheals
Loperamide HCl
N,N-Dimethyl(tera hydro-3,3-diphenyl)-2-furylidene ammonium bromide (furanuminium bromide)
37743-18-3
Antidiarrheals
Loperamide HCl
α,α-Diphenyl-γ-butyrolactone
956-89-8
Antidiarrheals
Loperamide HCl
4-Bromo-2-2-diphenylbutyric acid
37742-98-6
Antidiarrheals
Loratadine & Desloratadine
3-[2-(3Chlorophenyl) ethyl)-2-cyano pyridine
31255-57-9
Antihistamine
Loratadine & Desloratadine
8-Chloro-5,6 dihydro(11H)-benzo[5,6] cyclohepta (1,2b) pyridine -11-one
31251-41-9
Antihistamine
Loratadine & Desloratadine
8 Chloro-11-[(N-methyl)-4-piperidylidene]-6, 11-dihydro-5H-benzo [5,6]cyclohepta (1,2b) pyridine (methyl loratadine)
38092-89-6
Antihistamine
Loratadine & Desloratadine
{3-[2-(3-Chlorophenyl)ethyl]pyridine-2-yl}-(1-methyl piperidine-4-yl) (methanone HCl)
119770-60-4
Antihistamine
Loratadine & Desloratadine
N-Methyl-4-chloro piperidine
5570-77-4
Antihistamine
Losartan Potassium
2-N-Butyl-4chloro-1-[(2"-H tetrazol-5-yl)(1,1"-biphenyl)-4yl)methyl]-1H imidazole-5-methanol (losartan base)
11479-26-4
Anti-hypertensive
Losartan Potassium
2-N-Butyl-4-chloro-5-Formylimidazole (BCFI)
83857-96-9
Anti-hypertensive
Mirabegron
(R)-N-(4-nitrophenethyl)-2-hydroxy-2-phenylacetamide
521284-19-5
Antipasmodic
Mirabegron
(R)-2-(4-nitrophenethylamino)-1-phenylethanol.HCl
521284-21-9
Antipasmodic
Mirabegron
(R)-2-(4-aminophenethylamino)-1-phenylethanol
521284-22-0
Antipasmodic
Oxatomide
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one
62780-89-6
Antihistamine
Oxatomide
1-(Diphenyl methyl) piperazine
841-77-0
Antihistamine
Pemetrexed acid
4-(2-(2-amino-4-hydroxy-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoic acid
137281-39-1
Anti Cancer
Pimozide
4-(2-Keto-1-benzimidazolinyl) piperidine
20662-53-7
Antipsychotic
Pimozide
1-Chloro-4,4-di (4-fluorophenyl)butane
3312-04-7
Antipsychotic
Prucalopride
1-(3-Methoxy propyl) piperidine-4-one
16771-85-0
Gastroprokinetic
Prucalopride
1-(3-Methoxypropyl)-4-Piperidinamine
179474-79-4
Gastroprokinetic
Rifabutin
1-Isobutyl-4-piperidone
72544-16-2
Antibacterial
Rivaroxaban
4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone
446292-08-6
Antithromobotic
Rivaroxaban
4-(4-((S)-5-(Aminomethyl)-2-oxooxazolidin-3-Yl)phenyl)morpholin-3-one HCl
898543-06-1
Antithromobotic
Ropivacaine Hydrochloride Monohydrate
(S)-N-(2-6-dimetylphenyl)piperidine-2-carboxamide
27262-40-4
Local anesthetics
Rupatadine Fumarate
3-Chloromethyl-5-methyl pyridine HCl
1007089-84-0
Antihistamine
Selexipag
4-(Isopropylamino)butanol
42042-71-7
Vasodilator
Tamsulosin HCl
R-(-)-5-(2-Amino-propyl)-2-methoxy-benzenesulfonamide
112101-81-2
Alpha-1 adrenergic antagonist
Tamsulosin HCl
5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide
106133-20-4
Alpha-1 adrenergic antagonist
Trazadone
[1,2,4]triazolo[4,3-a]pyridin-3-one
6969-71-7
Antidepressant
Trazadone
1-(3-chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride
52605-52-4
Antidepressant
Tucatinib
N-(4-Amino-2-Cyanophenyl)-N,N-Dimethanimidamide
194423-17-1
Anticancer
Ormeloxifene hydrochloride Intermediate
rel-4-((3R,4R)-7-Methoxy-2,2-dimethyl-3-phenylchroman-4-yl)phenol
57897-46-8
—
Etodolac Intermediate
7-ethyl tryptophol
41340-36-7
—
Salcaprozate sodium intermediate
Ethyl 8-bromo octanate
29823-21-0
—
Prazosin.HCl, Terazosin.HCl, Alfuzosin.HCl, Doxazosin.HCl
2-Chloro-4-amino-6,7-dimethoxyquinazoline
23680-84-4
—
Minoxidil, Kopexil, Kopyrrol
2,4-Diamino-6-chloropyrimidine
156-83-2
—
Ticagrelor
4,6-Dichloro-2-(propylthio)pyrimidin-5-amine
145783-15-9
—
Ticagrelor
(1R,2S)-rel-2-(3,4-difluorophenyl)cyclopropanamine Hydrochloride
1156491-10-9
—
Ticagrelor
2-((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyl tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol L-tartaric acid
376608-65-0
—
Isoxsuprine HCl
4-(2-amino-1-hydroxypropyl)phenol hydrochloride
13062-82-3
—
Voglibose
Tetrabenzyl-voglibose
115250-39-0
—
Mitapivat Sulfate
1-Boc-piperazine
57260-71-6
—
Mitapivat Sulfate
tert-butyl 4-[4-(quinolin-8-ylsulfonylamino)benzoyl]piperazine-1-carboxylate
1260081-86-4
—
Mitapivat Sulfate
Cyclopropanecarboxaldehyde
1489-69-6
—
Ruxolitinib
(R)-3-(4-Bromo-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
1146629-83-5
—
Ruxolitinib
4-Chloro-7H-pyrrolo[2,3-d]pyrimidine
3680-69-1
—
Ruxolitinib
4-Bromo-1H-pyrazole
2075-45-8
—
Venetoclax
3,3-Dimethylcyclohexanone
2979-19-3
—
Venetoclax
1H-Pyrrolo[2,3-b]pyridin-5-ol
98549-88-3
—
Venetoclax
1-((2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl)methyl)piperazine
1228780-72-0
—
Venetoclax
2-((1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(4-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)benzoic acid
1235865-77-6
—
Upadacitinib
1-((Benzyloxy)carbonyl)-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid
1869118-25-1
—
Upadacitinib
dicyclohexylamine (3R,4S)-1-((benzyloxy)carbonyl)-4-ethylpyrrolidine-3-carboxylate
2095311-49-0
—
Olaparib
3-[(3,4-Dihydro-4-oxo-1-phthalazinyl)methyl]benzoic acid
420846-72-6
—
Olaparib
Cyclopropyl-1-piperazinylmethanone
59878-57-8
—
Atrasentan
Ethyl (2R,3R,4S)-2-(4-Methoxyphenyl)-4-[3,4-(methylenedioxy)phenyl]pyrrolidine-3-carboxylate
178739-03-2
—
Atrasentan
2-Bromo-N,N-dibutylacetamide
40124-27-4
—
Rimegepant Sulphate
7,8-Dihydro-5H-cyclohepta[b]pyridine-5,9(6H)-dione
39713-40-1
—
Rimegepant Sulphate
(5S,6S,9R)-6-(2,3-Difluorophenyl)-6,7,8,9-tetrahydro-9-[[tris(1-methylethyl)silyl]oxy]-5H-cyclohepta[b]pyridin-5-ol
1190363-50-8
—
Rimegepant Sulphate
1-Piperidin-4-yl-1,3-dihydroimidazo[4,5-b]pyridin-2-one dihydrochloride
781649-84-1
—
GalNAc
GalnAc-L96 TEA
1159408-61-3
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